Glycosyl compounds
Medchemexpress LLC IL-1 beta Canine T 50ug
IL-1 beta Protein Canine (Tag free) is the recombinant canine-derived IL-1 beta expressed by E coli with tag Free labeled tag
Medchemexpress LLC IKK alpha + IKK beta Antibody (YA349) | 87 kDa | 10 UL
IKKβ protein is a serine kinase crucial for the NF-kappa-B signaling pathway, activated by various stimuli including inflammatory cytokines and cellular stresses. As part of the canonical IKK complex, it mediates the conventional NF-kappa-B activation by phosphorylating inhibitors, leading to their degradation and allowing NF-kappa-B to activate gene transcription for immune response, growth control, and protection against apoptosis. IKKβ also phosphorylates other signaling components, regulating canonical IKKs and influencing diverse cellular processes.
- Rabbit-derived and non-conjugated IgG monoclonal antibody
- Targets IKK alpha + IKK beta
- Reactive with human and mouse samples
- Protein A affinity purified
- Predicted and observed molecular weight: 87 kDa
- Applications include WB, ICC/IF, IP
- Store at -20°C for 1 year, avoid repeated freeze/thaw cycles
- Shipped with blue ice
Medchemexpress LLC FSH beta protein, mouse (HEK293, Fc) | 95.0% | 42-60 kDa | 10 UG
The FSH beta protein, in conjunction with the alpha chain CGA, forms follitropin, also known as follicle-stimulating hormone (FSH). This hormone is crucial for follicle development and spermatogenesis within reproductive organs. It binds to FSHR, a G protein-coupled receptor on target cells, initiating downstream signaling pathways. The intricate assembly of FSH beta within the hormone heterodimer underscores its essential contribution to reproductive processes and hormonal signaling cascades.
- Appearance: Lyophilized powder
- Formulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% trehalose
- Endotoxin level: <1 EU/μg, determined by LAL method
- Storage: Stored at -20°C for 2 years from date of receipt
- Stability after reconstitution: Stable at 4°C for 1 week or -20°C for longer (with carrier protein)
Selleck Chemical LLC D 4476
D 4476 is a potent selective and cell-permeant CK1 (casein kinase 1) inhibitor with IC50 of 200 nM and 300 nM in a cell-free assay for CK1 from Schizosaccharomyces pombe and CK1 respectively Also acts as an ALK5 inhibitor with IC50 of 500 nM
Selleck Chemical LLC D 4476
D 4476 is a potent selective and cell-permeant CK1 (casein kinase 1) inhibitor with IC50 of 200 nM and 300 nM in a cell-free assay for CK1 from Schizosaccharomyces pombe and CK1 respectively Also acts as an ALK5 inhibitor with IC50 of 500 nM
Medchemexpress LLC Beta-Cortol | 667-65-2 | 99.9% | 368.51 | 1 ML
Beta-Cortol is an O-glycosylated compound and cortisol metabolite, isolated from the leaves of mulberry cultivar Yu 711. Its concentration significantly decreases when the plant is subjected to drought stress. It functions as a biomarker, as serum Beta-Cortol levels in early non-small cell lung cancer models are downregulated to 1/8 of the preoperative level after tumor resection. Due to these notable changes under specific pathological conditions, Beta-Cortol is broadly utilized in studies concerning early non-small cell lung cancer.
- O-glycosylated compound and cortisol metabolite.
- Isolated from the leaves of mulberry cultivar Yu 711.
- Concentration decreases significantly in plants under drought stress.
- Biomarker for early non-small cell lung cancer, with serum levels dropping to 1/8 of preoperative levels after tumor resection.
- Widely used in studies related to early non-small cell lung cancer.
Alkali Scientific 4 Nitrophenyl β D xylopyranoside, 1 G
4-Nitrophenyl β-D-xylopyranoside, 1g, is a widely used reagent in the biochemical analysis of xylanase and glycosidase activities. When hydrolyzed by these enzymes, it releases a p-nitrophenol group that can be detected using spectrophotometric methods. This compound is essential in studies focused on the breakdown of hemicellulose, particularly in biofuel production, where xylanases play a significant role in converting plant biomass into fermentable sugars. The 1g quantity is suitable for medium-scale experiments and is used in routine enzyme assays, carbohydrate metabolism studies, and biotechnological applications.
Crescent Chemical Co Inc NITROPHENYL-B-D-GALACTOPYRANOS
Nitrophenyl-b-D-galactopyranoside research grade Substrate for β-D-galactosidase. Size - 5G Storage Conditions - +2 °C TO +8 °C Catalog Number - 30710.02 CAS 369-07-3
Alkali Scientific 4 Nitrophenyl β D Glucopyranoside, 1 G
4-Nitrophenyl β-D-Glucopyranoside is a chromogenic substrate used to detect β-glucosidase activity in a variety of biological assays. The 1g pack provides a small-scale, concentrated source of this substrate, making it ideal for enzyme activity studies and microbiological research. When hydrolyzed by β-glucosidase, this compound undergoes a color change, providing a clear, visual indication of enzymatic activity. 4-Nitrophenyl β-D-Glucopyranoside is commonly used in studies involving carbohydrate metabolism and enzyme kinetics. It also serves as a substrate in diagnostic tests, offering a straightforward and efficient way to measure β-glucosidase activity in research applications.
![Alkali Scientific NPG [p Nitrophenyl β D glucuronide], 250 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660896.jpg-250.jpg)
Alkali Scientific NPG [p Nitrophenyl β D glucuronide], 250 Mg
NPG (p Nitrophenyl β D Glucuronide) is a widely used reagent for the detection of glucuronidase activity in biochemical assays. This substrate, when hydrolyzed by glucuronidase enzymes, releases a yellow-colored compound that can be quantified, making it ideal for enzyme activity measurements. NPG is commonly used in research on drug metabolism, liver function, and the role of glucuronidase in various biochemical processes. The 250 mg pack is well-suited for high-sensitivity assays and is an essential tool for laboratories studying the conjugation of glucuronides in both humans and animals. It’s also valuable in diagnostic assays for enzyme-linked immunosorbent assays (ELISA).
Medchemexpress LLC SDF-1 beta/CXCL12 H 2ug
SDF-1 beta (Stromal-derived factor-1 SDF-1 ) is a stromal derived CXC chemokine that signal through the CXCR4 receptor SDF-1 has chemotactic activity on B and T cells[1][2] SDF-1 beta/CXCL12 Protein Human (72a a) is produced in E coli and consists of 72 amino acids (K22-M93)
Medchemexpress LLC IL-12 beta Human H 2ug
IL-12 beta Protein also known as natural killer cell stimulatory factor 2 is a common subunit (p40) of IL-12 and IL-23 IL-12 is a inflammatory factor expressed by activated macrophages and involves in Th1-type immune response against cancer[1] IL-12 beta Protein located outside the cell membrane involves in singalling mediated by Jak-STAT[3] IL-12 beta Protein consists of 328 amino acids (M1-S328) with a fibronectin type-III domain (237-328 a a) IL-12 beta Protein Human (M1-S328) is produced in HEK293 cells with a C-Terminal Fc-tag
Medchemexpress LLC TGFBR2/TGF-beta RII 500ug | 500ug
TGFBR2/TGF-beta RII Protein collaborates with TGFBR1 to form a dedicated receptor for TGFB1 TGFB2 and TGFB3 It serves as a signal transducer orchestrating diverse physiological and pathological processes including cell cycle regulation mesenchymal cell dynamics wound healing matrix production immunosuppression and carcinogenesis Upon cytokine binding the receptor complex activates TGFBR1 through TGFBR2 phosphorylation initiating the canonical SMAD-dependent TGF-beta signaling cascade Additionally TGFBR2 participates in non-canonical SMAD-independent pathways TGFBR2/TGF-beta RII Protein Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque-derived TGFBR2/TGF-beta RII protein expressed by HEK293 with C-hFc labeled tag